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Use ESAs only for treatment of anemia due to concomitant myelosuppressive chemotherapy.
Epoetin injection is usually given by a doctor after a kidney dialysis treatment or in a hospital or clinic.
Pyrexia (42%); artificial kidney clotting during dialysis (8%); chills (7%).
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Sandoz, Celltron and Biocad have ongoing clinical trials for similarity testing of their rituximab biosimilars (clinicaltrials.
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In controlled clinical trials of patients with cancer, darbepoetin alfa and other ESAs increased the risks for death and serious adverse cardiovascular reactions.
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Patients were excluded if they were less than 18 years of age as of June 1, 2009; had unknown gender; or had a history of Darbepoetin alfa or Epoetin alfa subcutaneous (s.
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As of the early 200s, tests to detect the misuse of epoetin alfa by athletes are increasingly reliable.
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Of the 1801 patients with CKD in clinical studies of darbepoetin alfa, 44% were age 65 and over, while 17% were age 75 and over.
Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up.
Damage to the skin changes skin flora, resulting in more frequent colonization by staphylococci and gram-negative bacteria.
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Clearly, the trials did not yield convincing evidence of any consistent quality-of-life benefit that would appear to outweigh the increased risks of nonfatal myocardial infarction, nonfatal stroke, and death.
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Immediately and permanently discontinue epoetin alfa and administer appropriate therapy if a serious allergic or anaphylactic reaction occurs.
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