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Schizophrenia and familial high risk participants showed more pronounced LPFC deficits in response to negative social signals, and, among those with low LPFC activity, interpersonal conflict was related to the exacerbation of negative mood and psychotic symptoms the following day.
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Background: Recent work has shown that impaired social and role functioning in schizophrenia are vulnerability traits that can improve the prediction of impending illness.
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In healthy participants, higher ventral striatal presynaptic dopamine levels also promote goal-directed signatures in lateral prefrontal cortex.
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Results: We achieved 80% classification accuracy with the NeuCube using eyes-closed EEG data, with 82% of participants with TRS and 78% of participants with UTRS being correctly classified.
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